5 Hydroxytryptophan, 5-HTP, a natural amino acid extracted from the dried seeds of the Griffonia , an African leguminous shrub, has antidepressant, stress-reducing, sleep-improving and weight-loss properties by naturally raising serotonin levels and increasing the production of complex amines in the body’s blood.
The metabolic pathway of 5-HTP is a complex process involving the participation of several enzymes and compounds.
The first step in the metabolism of 5-HTP is the catalytic conversion of 5-HTP to 5-HT by AADC, an important neurotransmitter that is released from neurons into the synaptic gap where it binds to receptors that regulate neuronal activity.
Raw material source Of 5-HTP
Griffonia seeds are rich in 5-hydroxytryptophan, which is currently the main natural source for the manufacture of 5-HTP.
The dried seeds of Griffonia simplicifolia, a shrub in the legume family, are oblong, about 1.5 cm long and 1 cm wide, with dry black seed coat, wrinkles, and yellowish-green endosperm with a slight soybean flavor, and the dry seed weighs about 0.8 g. The seeds are used in the wild inGriffonia , Ivory Coast, Africa, and other parts of the world. Wild in Africa, Ghana, Ivory Coast and Togo and other West African countries, harvest time from December to February.






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